Patients should receive an initial intravenous bolus injection of mesna equal to 20 percent of the ifosfamide dose at the time of ifosfamide administration, followed by oral mesna tablets at 40 percent of the daily ifosfamide dose, administered at two and six hours following each dose of ifosfamide. Thus, the total daily mesna dose is 100 ... WebPatients received ifosfamide 4 g/m2 with mesna uroprotection on day 1, and cisplatin 25 mg/m2/d and etoposide 100 mg/m2/d on days 1, 2, and 3; courses were repeated every 28 days. Premedication with prochlorperazine, dexamethasone, and high-dose metoclopramide was given to prevent nausea; lorazepam was added on days 2 and 3 only.

Bone Cancer Treatment Regimens - Cancer Therapy Advisor

WebNov 21, 2024 · Mesna is a prescription medicine used to reduce the risk of inflammation and bleeding of the bladder (hemorrhagic cystitis) in people who receive ifosfamide (a medicine used to treat cancer). Mesna is not … WebThirty patients with advanced squamous cell carcinoma of the cervix were included in a phase II study with cisplatin (DDP) and ifosfamide (IF)/mesna. They received a median of 4 courses of chemotherapy and were all evaluable for response and toxicity. Each cycle consisted of 2 500 mg/m 2 IF i.v. days 1–5; mesna 500 mg/m 2 i.v. at hours 0 and ... csw ucla

TESTICULAR CANCER TREATMENT REGIMENS (Part 1 of 2)

WebCisplatin and paclitaxel can cause nerve damage (neuropathy), which can lead to numbness and tingling in the hands and feet. Cisplatin can also cause and kidney … WebBackground/aim: Cisplatin (CIS) is an effective antineoplastic agent used in the treatment of several cancer types. Peripheral neuropathy is a major dose-limiting side-effect in CIS therapy.... WebMesna partially alleviated redox imbalance, reduced the proinflammatory cytokines, and MMP-2/9 levels. Mesna administration also relieved the morphological changes in DRG … cryptofarm bsc