Phloretin hydrolase
WebbPhloretin hydrolase SpringerLink Enzyme Handbook 4 pp 1131–1134 Cite as Phloretin hydrolase Dietmar Schomburg & Margit Salzmann Chapter 16 Accesses Keywords Molecular Weight Crystall Ization Bond Cleavage Aspergillus Niger Catalysed Reaction These keywords were added by machine and not by the authors. WebbPhloretin Hydrolase. Chemicals and Non-standard biopolymers (4 molecules) 1. 2. MAGNESIUM ION. 2. 2. 1,2-ETHANEDIOL * Click molecule labels to explore molecular sequence information. Citing MMDB. Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
Phloretin hydrolase
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Webb1 okt. 2004 · The phloretin hydrolase was heterologously expressed in Escherichia coli and purified. The molecular mass of the native enzyme was approximately 55 kDa as … Webb16 okt. 2024 · It possesses a phloretin-hydrolase able to break the phloretine C-C bond . Another anaerobic bacterium isolated from human feces, Clostridium orbiscindens, was found to degrade apigenin to 3-(4-hydroxyphenyl)propionic acid with phloretin and naringenin as the two intermediates .
Webb19 feb. 2024 · Two members of the PhlG family have been separately identified as 2,4-diacetylphloroglucinol (2,4-DAPG) hydrolase and phloretin hydrolase; however, the extent of functional divergence and catalytic substrates for … Webb1 mars 2014 · Phloretin hydrolase catalyzes the hydrolytic C-C cleavage of phloretin to phloroglucinol and 3-(4-hydroxyphenyl)propionic acid during flavonoid degradation in Eubacterium ramulus.
Webb1 apr. 2024 · Two members of the PhlG family have been separately identified as 2,4-diacetylphloroglucinol (2,4-DAPG) hydrolase and phloretin hydrolase; however, the extent of functional divergence and catalytic substrates for most members of this family is still unknown ... Macromolecules Find similar proteins by: (by identity cutoff) 3D Structure WebbInhibitor in Enzyme-catalyzed Reactions (18 results) compound shows little anti-Staphylococcus aureus activity, but significantly inhibit SrtB activity in vitro. Phloretin reduces human alveolar epithelial cell damage caused by Staphylococcus aureus. Phloretin directly localizes in the active pocket of SrtB and blocks substrate binding.
WebbAs the aglycone of phloridzin, phloretin belongs to dihydrochalcone with antioxidant, anti-inflammatory and antimicrobial activities. In this study, multispectroscopic techniques …
Webb1 jan. 2006 · However, both phloretin hydrolase and DAPG hydrolase show no sequence similarity to other known C-C hydrolase enzymes and contain no motifs typical of the α/β-hydrolase-fold superfamily as determined by a search of the ESTHER database (19, 41; C. Keel and M. Bottiglieri, unpublished findings). greeneview high school calendarWebbAlso hydrolyses other C-acylated phenols related to phloretin. Isolated from the fungus Aspergillus niger and the bacteria Pantoea agglomerans and Eubacterium ramulus. History. EC 3.7.1.4 created 1972, modified 2024. Pathway. ec00946. Degradation of flavonoids. ec01100. Metabolic pathways. fluid in the brainWebbPhloroglucinol is an organic compound with the formula C 6 H 3 (OH) 3.It is a colorless solid. It is used in the synthesis of pharmaceuticals and explosives.Phloroglucinol is one of three isomeric benzenetriols.The other two isomers are hydroxyquinol (1,2,4-benzenetriol) and pyrogallol (1,2,3-benzenetriol). Phloroglucinol, and its benzenetriol isomers, are still … greeneview high school ohioWebb2 nov. 2010 · Description. Autosomal recessive, rare and severe gastrointestinal disorder. It is characterized by watery diarrhea in infants fed with breast milk or other lactose … greeneview localWebbLactase-phlorizin hydrolase may refer to: Phloretin hydrolase, an enzyme Glycosylceramidase, an enzyme This set index page lists enzyme articles associated … greeneview high school wikipediaWebbphloretin hydrolase1-[2,4,6-tris(oxidanyl)phenyl]ethanone. NCBI. National Center for Biotechnology Information. Search. 5XEY: Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus. PDB ID: 5XEY Download: MMDB ID: 161436: PDB Deposition Date: 2024/4/6: Updated in MMDB: 2024/05: fluid in the body symptomsWebb1 feb. 2024 · Phloretin hydrolysis as carried out by phloretin hydrolase [25, 26] and the three-step conversion of daidzein to equol [27][28][29] are relatively well studied, while gut bacterial enzymes ... fluid in the brain symptoms