Shumiya cataract rat

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WebAug 20, 2024 · The lens of cataract rats had α-A crystallin expression levels increased by 35% when compared to the control (Fig. 2E). ... Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat. J. Clin. Invest., 116 (2006), pp. 395-404. CrossRef View Record in Scopus Google Scholar WebJun 1, 2006 · Search life-sciences literature (Over 39 million articles, preprints and more)

The Intravitreal Injection of Lanosterol ... - Semantic Scholar

WebDelay of cataract development in the Shumiya cataract rat by water containing enhanced concentrations of magnesium and calcium Curr Eye Res. 2007 May;32(5):439-45. doi: … WebPurpose: To conduct a long-term observation study of SCR rats that had developed a mature cataract at 11 weeks of age at 3-month intervals until the rats were 12 months old. Methods: Lenses of 15 rats were examined with both light and electron microscopes.. Results: At 12 weeks, opacity was observed in the perinuclear zone and the cortical intermediate layer. cz assembly\u0027s

Lens reconstruction after mature cataract in SCR rat.

WebInomata M, Hayashi M, Shumiya S, Kawashima S, Ito Y. Aminoguanidine-treatment results in the inhibition of lens opacification and calpain-mediated proteolysis in Shumiya Cataract Rats (SCR). J Biochem. 2000;128(5):771–776. 41. WebαB-crystallin decreased with age in lens ﬁbres of cataract rats. Calpains (µ- and m-), 20S proteasome, dipeptidyl peptidases II and III and soluble alanyl aminopeptidase are … WebWe previously found that the increases in Ca 2+ content in the lenses of three hereditary cataract model rats, UPL rat (UPLR), Shumiya cataract rat (SCR) and Ihara cataract rat (ICR), are inhibited by aminoguanidine, a selective inhibitor of inducible nitric oxide synthase, and that the mechanisms of Ca 2+ enhancement in these rat models differ. In this study, we … czateria google play

Comparison of the Mechanisms of Cataract Development ... - 日本 …

SCR (Shumiya Cataract Rat) - Kyoto U

WebThe Shumiya cataract rat (SCR) is a hereditary cataractous strain. It is thought that the continuous occur-rence of poorly differentiated epithelial cells at the bow area of the lens … czas surferow filmwebWebLens reconstruction after mature cataract in SCR rat. @article{Okano1999LensRA, title={Lens reconstruction after mature cataract in SCR rat.}, author={Takuya Okano and Shigekazu Uga and S. Ishikawa and Akiko Hara and Seigou Shumiya}, journal={Japanese journal of ophthalmology}, year={1999}, volume={43 5}, pages={ 363-7 } } czatbing.com

"Webchestnut (Trapa bispinosa Roxb.) extract (TBE) on cataracts and the expression of antioxidant-related genes were assessed in Shumiya cataract rats (SCRs). LU+TBE or castor oil (COil) as a control was administered to 6- or 9-week-old cataractous SCRs and noncataractous SCRs via a feeding needle for 3 or 4 weeks. " - Shumiya cataract rat

Shumiya cataract rat

Involvement of inducible nitric oxide synthase in cataract …

Web遺伝性白内障ラットのSCR（Shumiya Cataract Rat）は高血圧自然発症ラットに肥満遺伝子を導入したコンジェニック系のSHR-faを育成中、成熟期に核性白内障をおこすライン … Webcataract drug for human cataracts has not yet been intro-duced. In studies to develop anti-cataract drugs, the selection of the experimental animal is very important. The UPL rat (UPLR), Shumiya cataract rat (SCR) and Ihara cataract rat (ICR/f; ICR) are hereditary cataractous strains, and it has been shown that these rats provide useful models ...

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WebNov 1, 1993 · The Shumiya cataract rat (SCR) is a hereditary cataract model in which lens opacity appears spontaneously in the nuclear and perinuclear portions at 11–12 weeks of … WebFeb 1, 2024 · @article{Nagai2024TheII, title={The Intravitreal Injection of Lanosterol Nanoparticles Rescues Lens Structure Collapse at an Early Stage in Shumiya Cataract Rats}, author={Noriaki Nagai and Yuya Fukuoka and Kanta Sato and Hiroko Otake and Atsushi Taga and Mikako Oka and Noriko Hiramatsu and Naoki Yamamoto}, journal={International …

WebNov 2, 2024 · The Shumiya cataract rat (SCR) is a model for hereditary cataract. Two-thirds of these rats develop lens opacity within 10-11 weeks. Onset of cataract is attributed to … WebThe Shumiya cataract rat (SCR) is a hereditary cataract model in which lens opacity appears spontaneously in the nuclear and perinuclear portions at 11-12 weeks of age.

WebThe role of proteolytic enzymes in Shumiya cataract rats in alterations to lens proteins during cataract formation was studied immunohistochemically using antibodies against exopeptidases, such as lysosomal dipeptidyl peptidase II (DPP II), cytosolic dipeptidyl peptidase III, and soluble and membrane-bound alanyl aminopeptidases, and against … WebFeb 1, 2006 · The Shumiya cataract rat (SCR) and normal control rat strains of NC1 and NC2 were established. Mean cataract appearance in adult SCR rats was 66.7%, and embryo …

WebSpecifically, hypomorphic LSS and farnesyl diphosphate farnesyl transferase 1 (FDFT1) mutations lower cholesterol and induce cataracts in the Shumiya cataract rat . More recently, Zhao et al. [47] identified two novel LSS mutations, G588S and W581R, from those with congenital cataracts, and treatment with lanosterol eye drops was shown to …

WebAug 4, 2024 · Six-week-old Shumiya cataract rats were used to perform experiments. The right eye of each rat was injected with TAT-HA-Prdx6 WT-NPs or TAT-HA-Prdx6 K122/142R-NPs, whereas the left eyes were administered with TAT-HA-Prdx6 Inactive-mutant-NPs. The subconjuctival injection was made using micro-syringes fitted with 30-gauge needles. czasy conditionalWebJul 21, 2024 · We previously designed ophthalmic nanosuspensions of LAN (LAN-ONSs) and reported that repeated instillation of LAN-ONSs attenuated the slight collapse of the lens structure in Shumiya cataract rats (SCR), although the serious structural collapses were not reversed with the instillation of LAN-ONSs, and repeated instillation could not reverse or ... bingham real estateWebJul 4, 2024 · Ophthalmic In Situ Gelling System Containing Lanosterol Nanoparticles Delays Collapse of Lens Structure in Shumiya Cataract Rats. Next Article in Special Issue. Studies on the Effect of Oil and Surfactant on the Formation of Alginate-Based O/W Lidocaine Nanocarriers Using Nanoemulsion Template. czas to be going toWebApr 1, 2007 · Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat. Mori M, Li G, Abe I, Nakayama J, Guo Z, Sawashita … czat gtp onlineWebThe Shumiya cataract rat (SCR) is a hereditary cataractous strain. It is thought that the continuous occur-rence of poorly differentiated epithelial cells at the bow area of the lens forms the pathophysiological basis for cataract formation in SCRs. In this study, we attempted to identify the genes associated with cataract cza the oneWebWe demonstrate a delaying effect of deep-sea drinking water (DDW) containing enhanced magnesium ion (Mg 2 +) and calcium ion (Ca 2 +) concentrations on cataract … cz a.s. v preze .380 from world war 2Web开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 czat home.pl